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潘翔2022级生物化学与分子生物学博士研究生

个人简介

2022级生物化学与分子生物学博士研究生

研究领域

肿瘤非编码RNA调控新机制。发现及鉴定了一批参与细胞周期调控、肿瘤发生及转移相关的microRNA/circRNA,并对其功能表型、作用机制及临床转化潜力进行深入研究。

既往成果

Menin促进前列腺癌侵袭与转移的机制研究。黑龙江省自然科学基金(课题编号:YQ2023H015)(参与)

医联体模式下扬州农村地区前列腺癌筛查的探索。2022年扬州市科技计划项目(课题编号:YZ2022267)(课题负责人)

快速检测TURP术中出血量的临床研究。2017年深圳市卫生计生系统科研项目(No.SZFZ2017035)(参与)

miRNAs作为肾癌预后标志物的研究。2018年深圳市卫生计生系统临床研究项目(No.SZLY2018023)(参与)

鼻咽癌侵袭和复发的标记物筛选及功能鉴定研究。2019年深圳市科创委基础研究学科布局(参与)

代表期刊

Pan, X., Jin, L., He, T., Hu, J., Quan, J., Zhou, L., Ni, L., Yang, S., Mao, X., & Lai, Y. (2016). Mucinous adenocarcinoma of the bladder: A case report and review of the literature. Molecular and clinical oncology, 5(4), 447–448.

Pan, X., Quan, J., Zhao, L., Li, W., Wei, B., Yang, S., & Lai, Y. (2018). Xp11.2 translocation renal cell carcinoma with TFE3 gene fusion: A case report. Molecular and clinical oncology, 8(1), 83–85.

Pan, X., Quan, J., Li, Z., Zhao, L., Zhou, L., Xu, J., Xu, W., Guan, X., Li, H., Yang, S., Gui, Y., & Lai, Y. (2018). miR-566 functions as an oncogene and a potential biomarker for prognosis in renal cell carcinoma. Biomedicine & pharmacotherapy, 102, 718–727.

Pan, X., Li, Z., Zhao, L., Quan, J., Zhou, L., Xu, J., Xu, W., Guan, X., Li, H., Yang, S., Gui, Y., & Lai, Y. (2018). microRNA‑572 functions as an oncogene and a potential biomarker for renal cell carcinoma prognosis. Oncology reports, 40(5), 3092–3101.

Pan, X., Zhao, L., Quan, J., Liu, K., Lai, Y., Li, Z., Zhang, Z., Xu, J., Xu, W., Guan, X., Li, H., Yang, S., Gui, Y., Chen, Y., & Lai, Y. (2019). MiR-378a-5p acts as a tumor suppressor in renal cell carcinoma and is associated with the good prognosis of patients. American journal of translational research, 11(4), 2207–2218.

Pan, X., He, T., Peng, X., Li, H., Zhang, F., & Lai, Y. (2020). miR-638 acts as an oncogene and predicts poor prognosis in renal cell carcinoma. American journal of translational research, 12(7), 3645–3659.

Li, H., Pan, X., Gui, Y., Quan, J., Li, Z., Zhao, L., Guan, X., Xu, J., Xu, W., & Lai, Y. (2019). Upregulation of miR-183-5p predicts worse survival in patients with renal cell cancer after surgery. Cancer biomarkers : section A of Disease markers, 24(2), 153–158.(共一)

Liu, K., Pan, X., Peng, X., Zhang, C., Li, H., Guan, X., Xu, W., Xu, J., Zhao, L., Wang, T., & Lai, Y. (2019). Associations of high expression of miR-106b-5p detected from FFPE sample with poor prognosis of RCC patients. Pathology, research and practice, 215(6), 152391. (共一)

Peng, X., Pan, X., Liu, K., Zhang, C., Zhao, L., Li, H., Guan, X., Xu, W., Xu, J., Zhang, F., & Lai, Y. (2019). miR-142-3p as a novel biomarker for predicting poor prognosis in renal cell carcinoma patients after surgery. The International journal of biological markers, 34(3), 302–308. (共一)

Zhang, C., Pan, X., Peng, X., Liu, K., Wang, J., Zhao, L., Chen, X., Huang, G., Li, H., Ye, J., & Lai, Y. (2021). miR-30b-5p up-regulation related to the dismal prognosis for patients with renal cell cancer. Journal of clinical laboratory analysis, 35(2), e23599. (共一)

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