徐康博士，主要研究方向为生物医学信息学，免疫信息学和表观遗传学。于2024年在哈尔滨医科大学获生物医学工程博士学位，博士导师为徐娟教授，曾获黑龙江省优秀毕业生。2024年通过校优秀人才计划加入哈尔滨医科大学医工交叉学院并获得伍连德校长奖学金。目前主要从事单细胞免疫分析、单细胞基因组和转录组变异分析，主要研究成果发表于Molecular Cancer、Nucleic Acids Research、Briefings in Bioinformatics、Cancer Research等国际高水平生命科学杂志，参与多项国家级和省级科研项目。

教育经历

2021.09-2024.06 哈尔滨医科大学 生物医学工程 博士

2014.09-2021.06 哈尔滨医科大学 基础医学七年制 学士、硕士

工作经历

2024.07-至今 哈尔滨医科大学 医工交叉学院 讲师

代表性论文

1. Kang Xu#, Yangyang Cai#, Mengying Zhang#, Haozhe Zou, Zhenghong Chang, Donghao Li, Jing Bai*, Juan Xu* and Yongsheng Li*. Pan-cancer characterization of expression and clinical relevance of m6A-related tissue-elevated long non-coding RNAs. Molecular Cancer, 2021. 20(1): p. 31.

2. Kang Xu#, Xiyun Jin#, Ya luo#, Dezhong Lv, Liping Wang, Limei Fu, Yangyang Cai, Tingting Shao*, Yongsheng Li* and Juan Xu*. Spatial transcriptome analysis of long non-coding RNAs reveals tissue specificity and functional roles in cancer. Journal of Zhejiang University. Science. B., 2023 Jan 15;24(1):15-31.

3. Dezhong Lv#, Kang Xu#, Changbo Yang#, Yujie Liu, Ya Luo, Weiwei Zhou, Haozhe Zou, Yangyang Cai, Na Ding, Xia Li*, Tingting Shao*, Yongsheng Li*, Juan Xu*. PRES: a webserver for decoding the functional perturbations of RNA editing sites.  Briefings in Bioinformatics. 2022 Jul 18;23(4):bbac242.

4. Dezhong Lv#, Kang Xu#, Xiyun Jin#, Junyi Li, Yuchen Shi, Mengying Zhang, Xiaoyan Jin, Yongsheng Li, Juan Xu* and Xia Li*. LncSpA: LncRNA Spatial Atlas of Expression across Normal and Cancer Tissues. Cancer Research. 2020 May 15;80(10):2067-2071.

5. Mengying Zhang#, Kang Xu#, Limei Fu#, Qi Wang, Zhenghong Chang, Haozhe Zou, Yan Zhang*, Yongsheng Li*. Revealing Epigenetic Factors of circRNA Expression by Machine Learning in Various Cellular Contexts. iScience. 2020 Nov 24;23(12):101842.

6. Changbo Yang# , Yujie Liu# , Chongwen Lv# , Mengjia Xu , Kang Xu , Jingyi Shi , Tingting Tan , Weiwei Zhou , Dezhong Lv , Yongsheng Li* , Juan Xu* , Tingting Shao*. CanCellVar: A database for single-cell variants map in human cancer. American journal of human genetics， 2024 Jul 11;111(7):1420-1430.

7. Zishan Wang#, Jiaqi Yin#, Weiwei Zhou#, Jing Bai, Yunjin Xie, Kang Xu, Xiangyi Zheng, Jun Xiao, Li Zhou, Xiaolin Qi*, Yongsheng Li*, Xia Li*, Juan Xu*. Complex impact of DNA methylation on transcriptional dysregulation across 22 human cancer types. Nucleic Acids Research. 2020 Mar 18;48(5):2287-2302.

8. Dezhong Lv#, Zhenghong Chang#, Yangyang Cai#, Junyi Li, Liping Wang, Qiushuang Jiang, Kang Xu, Na Ding, Xia Li*, Juan Xu*, Yongsheng Li*. TransLnc: a comprehensive resource for translatable lncRNAs extends immunopeptidome.  Nucleic Acids Research. 2022 Jan 7;50(D1):D413-D420.

9. Weiwei Zhou#, Minghai Su#, Tiantongfei Jiang#, Qingyi Yang, Qisen Sun, Kang Xu, Jingyi Shi, Changbo Yang, Na Ding*, Yongsheng Li*, Juan Xu*. SORC: an integrated spatial omics resource in cancer.  Nucleic Acids Research. 2024 Jan 5;52(D1):D1429-D1437.

获奖情况

1. 第四届全国“农业、健康与生态”整合生物信息学大会研究生论坛最佳报告奖（2023.08）

2. 黑龙江省优秀毕业生（2024.06）

3. 哈尔滨医科大学三好学生（2024.06）

4. 哈尔滨医科大学伍连德校长奖学金（2024.07）