2018年药理教研室发表SCI论文60篇，1篇收录于J Am Coll Cardiol杂志(IF=19.896)；1篇收录于Nature communications (IF=12.353)，1篇收录于Circulation Research (IF=15.211)，1篇收录于Cancer Res(IF=9.130)。影响因子10.0以上4篇，5.0以上28篇，目前累计SCI影响因子341。

1.Benzhi Cai, Wenya Ma, Fengzhi Ding, Lai Zhang, Qi Huang, Xiuxiu Wang, Bingjie Hua,, Juan Xu, Jiamin Li, Chongwei Bi, Shuyuan Guo, Fan Yang, , Zhenbo Han, Yuan Li, GegeYan, Ying Yu, Zhengyi Bao, Meixi Yu, Faqian Li, , Ye Tian,, Zhenwei , Baofeng Yang, , The long noncoding RNA CAREL controls cardiac regeneration. J Am Coll Cardiol. 2018 Jul 31;72(5):534-550. .（IF 19.896）

2.Yong Zhang#, Lihua Sun#, Lina Xuan#, Zhenwei Pan, Xueling Hu, Hongyu Liu, Yunlong Bai, Lei Jiao, Zhange Li, Lina Cui, Xiaoxue Wang, Siqi Wang, Tingting Yu, Bingbing Feng, Ying Guo, Zonghong Liu, Weixin Meng, Hequn Ren, Jiyuan Zhu, Xuyun Zhao, Chao Yang, Ying Zhang, Chaoqian Xu, Zhiguo Wang, Yanjie Lu, Hongli Shan & Baofeng Yang. Long non-coding RNA CCRR controls cardiac conduction via regulating intercellular coupling. Nature Communications. 2018; 9:4176.[SCI IF: 12.353]

3.Zhang, Y., et al., LncRNA ZFAS1 as a SERCA2a Inhibitor to Cause Intracellular Ca2+ Overload and Contractile Dysfunction in a Mouse Model of Myocardial Infarction. Circ Res, 2018 May 11;122(10):1354-1368.（IF 15.211）

4.Liu S, Fan Y, Chen A, Jalali A, Minami K, Ogawa K, Nakshatri H,Li BY, Yokota H.

Osteocyte-Driven Downregulation of Snail Restrains Effects of Drd2 Inhibitors on Mammary Tumor Cells. Cancer Res. 2018 Jul 15;78(14):3865-3876. doi: 10.1158/0008-5472.CAN-18-0056. Epub 2018 May 16.（IF 9.130）

5.Haihai Liang,YAP1/Twist promotes fibroblast activation and lung fibrosis that conferred by miR-15a loss in IPF.Cell Death and Differentiation. 2018.(Accepted,IF=8.000)

6.Gao, J.L., et al., Characterizations of mitochondrial uncoupling induced by chemical mitochondrial uncouplers in cardiomyocytes. Free Radic Biol Med, 2018 Jun 20;124:288-298.（IF 6.020）

7.Li, Q., et al., Anagliptin inhibits neointimal hyperplasia after balloon injury via endothelial cell-specific modulation of SOD-1/RhoA/JNK signaling in the arterial wall. Free Radic Biol Med, 2018. 121: p. 105-116.（IF 6.020）

8.Li, X., et al., Aspirin Reduces Cardiac Interstitial Fibrosis by Inhibiting Erk1/2-Serpine2 and P-Akt Signalling Pathways. Cell Physiol Biochem, 2018. 45(5): p. 1955-1965.（IF 5.500）

9.Li, X., et al., lncRNA PFAL promotes lung fibrosis through CTGF by competitively binding miR-18a. FASEB J, 2018: p. fj201800055R.（IF 5.595）

10.Liang Haihai, Pan Zhenwei, Zhao Xiaoguang, Liu Li, Sun Jian, Su Xiaomin, Xu Chaoqian, Zhou Yuhong, Zhao Dandan, Xu Bozhi, Li Xuelian, Yang Baofeng,Lu Yanjie, Shan Hongli. LncRNA PFL contributes to cardiac fibrosis by acting as a competing endogenous RNA of let-7d. Theranostics, 2018.2, 8(4): 1180~1194.（IF 8.537）

11.Liang, H., et al., Systematic analyses reveal long non-coding RNA (PTAF)-mediated promotion of EMT and invasion-metastasis in serous ovarian cancer. Molecular Cancer, 2018 Jun 21;17(1):96（IF 7.776）

12.Lv, L., et al., The lncRNA Plscr4 Controls Cardiac Hypertrophy by Regulating miR-214. Mol Ther Nucleic Acids, 2018. 10: p. 387-397.（IF 5.660）

13.Qiu, F., et al., Pharmacological inhibition of SUMO-1 with ginkgolic acid alleviates cardiac fibrosis induced by myocardial infarction in mice. Toxicol Appl Pharmacol, 2018. 345: p. 1-9.（IF 3.616）

14.Sun, L.L.,et al., Myocardial infarction-induced hippocampal microtubule damage by cardiac originating microRNA-1 in mice. J Mol Cell Cardiol. 2018 Jul;120:12-27.（IF 6.020）

15.Xiao, X.L., et al., Niclosamide inhibits vascular smooth muscle cell proliferation and migrationmitochondrialand attenuates neointimal hyperplasia in injured rat carotid arteries. Br J Pharmacol, 2018. 175(10): p. 1707-1718.（IF 6.810）

16.Yu, M., et al., YAP1 contributes to NSCLC invasion and migration by promoting Slug transcription via the transcription co-factor TEAD. Cell Death Dis, 2018. 9(5): p. 464.（IF 5.638）

17.Zhao, D., et al., Cardiomyocyte Derived miR-328 Promotes Cardiac Fibrosis by Paracrinely Regulating Adjacent Fibroblasts. Cell Physiol Biochem, 2018. 46(4): p. 1555-1565.（IF 5.500）

18.Zhao, X., et al., Melatonin Protects against Lung Fibrosis by Regulating the Hippo/YAP Pathway. International Journal of Molecular Sciences, 2018. 19(4): p. 1118.（IF 3.687）

19.Ming-Jing Duan, Mei-Ling Yan, Qin Wang, Meng Mao, Dan Su, Lin-Lin Sun, Ke-Xin Li, Yang Qu, Qiang Sun, Xin-Yu Zhang, Si-Yu Huang, Ji-Chao Ma, Tao Ban*,Jing Ai*. Overexpression of miR-1 in the heart attenuates hippocampal synaptic vesicle exocytosis by the posttranscriptional regulation of SNAP-25 through the transportation of exosomes. Cell Commun Signal. 2018 Nov 29;16(1):91. doi: 10.1186/s12964-018-0303-5.（IF 5.324）

20.Ma JC, Duan MJ, Li KX, Biddyut D, Zhang S, Yan ML, Yang L, Jin Z, Zhao HM, Huang SY, Sun Q, Su D, Xu Y, Pan YH,Ai J.Knockdown of MicroRNA-1 in the Hippocampus Ameliorates Myocardial Infarction Induced Impairment of Long-Term Potentiation. Cell Physiol Biochem. 2018 Oct 25;50(4):1601-1616. doi: 10.1159/000494657(IF 5.500）

21.Rong Zhang, Yi Xu, Huifang Niu, Ting Tao,Tao Ban, Linyao Zheng,Jing Ai.Lycium barbarum polysaccharides restore adverse structural remodeling and cardiac contractile dysfunction induced by overexpression of microRNA-1. J Cell Mol Med. 2018; May, 1–10. 10.1111/jcmm.13740（IF 4.302）

22.Pan Z, Ai T, Chang PC, Liu Y, Liu J, Maruyama M, Homsi M, Fishbein MC, Rubart M, Lin SF, Xiao D, Chen H, Chen PS, Shou W, Li BY. Atrial Fibrillation and electrophysiology in Transgenic Mice with Cardiac-Restricted Overexpression of FKBP12. Am J Physiol Heart Circ Physiol. 2018 Nov 30. doi: 10.1152/ajpheart.00486.2018.（IF 3.654）

23.Sun YL, Li PH, Shi L, Su WZ, Li DS, Xue GL, Zhao Y, Li CZ, Li Y, Zhou Y, Li SX, Zhang Y, Lu YJ,Pan ZW. Valsartan reduced the vulnerability to atrial fibrillation by preventing action potential prolongation and conduction slowing in castrated male mice. J Cardiovasc Electrophysiol. 2018 Jul 17. doi: 10.1111/jce.13697.（IF 3.068）

24.Zhang Y, Zhang YY, Li TT, Wang J, Jiang Y, Zhao Y, Jin XX, Xue GL, Yang Y, Zhang XF, Sun YY, Zhang ZR, Gao X, Du ZM, Lu YJ, Yang BF,Pan ZW.Ablation of interleukin-17 alleviated cardiac interstitial fibrosis and improved cardiac function via inhibiting long non-coding RNA-AK081284 in diabetic mice. J Mol Cell Cardiol. 2018 Jan 3. pii: S0022-2828(18)30001-4. doi: 10.1016/j.yjmcc.2018.01.001.（IF 5.218）

25.Guan J, Zhao M, He C, Li X, Li Y, Sun J, Wang W, Cui YL, Zhang Q,Li BY, Qiao GF. Anti-Hypertensive Action of Fenofibrate via UCP2 Upregulation Mediated by PPAR Activation in Baroreflex Afferent Pathway. Neurosci Bull. 2018 Sep 1. doi: 10.1007/s12264-018-0271-1.（IF 3.155）

26.Xu WX, Yu JL, Feng Y, Yan QX, Li XY, Li Y, Liu Z, Wang D, Sun X, Li KX, Wang LQ,Qiao GF, Li BY.Spontaneous activities in baroreflex afferent pathway contribute dominant role in parasympathetic neurocontrol of blood pressure regulation. CNS Neurosci Ther. 2018 Dec;24(12):1219-1230. doi: 10.1111/cns.13039. Epub 2018 Jul 25.（IF 3.495）

27.Yuan M, Ma MN, Wang TY, Feng Y, Chen P, He C, Liu S, Guo YX, Wang Y, Fan Y, Wang LQ, E XQ,Qiao GF, Li BY.Direct activation of tachykinin receptors within baroreflex afferent pathway and neurocontrol of blood pressure regulation. CNS Neurosci Ther. 2018 Jun 13. doi: 10.1111/cns.12993. [Epub ahead of print]（IF 3.495）

28.Wang L, Wang Y, Chen A, Jalali A, Liu S, Guo Y, Na S, Nakshatri H,Li BY,Yokota H. Effects of a checkpoint kinase inhibitor, AZD7762, on tumor suppression and bone remodeling. Int J Oncol. 2018 Sep;53(3):1001-1012. doi: 10.3892/ijo.2018.4481. Epub 2018 Jul 13.（IF 3.333）

29.Chen A, Wang L, Liu S, Wang Y, Liu Y, Wang M, Nakshatri H,Li BY,Yokota H. Attraction and Compaction of Migratory Breast Cancer Cells by Bone Matrix Proteins through Tumor-Osteocyte Interactions. Sci Rep. 2018 Apr 3;8(1):5420. doi: 10.1038/s41598-018-23833-1.（IF 4.122）

30.Jiang YN#, Du WJ#, Chu Q#, Qin Y, Tuguzbaeva G, Wang H, Li AQ, Li GY, Li YY, Chai L, Yue E, Sun X, Wang ZG, Pavlov V, Yang BF*,Bai YL*. Downregulation of Long Non-Coding RNA Kcnq1ot1: An Important Mechanism of Arsenic Trioxide-Induced Long QT Syndrome. Cell Physiol Biochem. 2018;45(1):192-202. doi: 10.1159/000486357. Epub 2018 Jan 15.( IF:5.5)

31.Xian HM, Che H, Qin Y, Yang F, Meng SY, Li XG,Bai YL*, Wang LH*. Coriolus versicolor aqueous extract ameliorates insulin resistance with PI3K/Akt and p38 MAPK signaling pathways involved in diabetic skeletal muscle. Phytother Res. 2018 Mar;32(3):551-560. doi: 10.1002/ptr.6007. Epub 2017 Dec 15.(IF:3.349)

32.Bai Y#*, Sun X#, Chu Q, Li A, Qin Y, Li Y, Yue E, Wang H, Li G, Zahra SM, Dong C, Jiang Y*. Caspase-1 regulate AngII-induced cardiomyocyte hypertrophy via upregulation of IL-1β. Biosci Rep. 2018 Feb 12. pii: BSR20171438. doi: 10.1042/BSR20171438. [Epub ahead of print]( IF:2.899)

33.Jiang Y, Chai L, Fasae MB,Bai Y*. The role of HIV Tat protein in HIV-related cardiovascular diseases. J Trans Med. 2018;16:121.(IF: 4.197)

34.Chu Q#, Li AQ#, Chen X#, Qin Y, Sun X, Li YY, Yue E, Wang Chao, Ding XY, Yan Y, Zahra SM, Wang S, Jiang YN,Bai YL*, Yang BF*. Overexpression of miR-135b attenuates pathological cardiac hypertrophy by targeting CACNA1C. Int J Cardiol. 2018 (accepted)( IF : 4.034)

35.Yang F, Qin Y, Lv J, Wang YQ, Che H, Chen X, Jiang YN, Li AQ, Sun X, Yue E, Ren L, Li Y,Bai YL*, Wang LH. Silencing long non-coding RNA Kcnq1ot1 alleviates pyroptosis and fibrosis in diabetic cardiomyopathy. Cell Death Dis. 2018 accepted.(IF: 5.638)

36.Yang F, Qin Y, Wang YQ, Li AQ, Lv J, Sun X, Che H, Han TS, Meng SY,Bai YL*, Wang LH. LncRNA Kcnq1ot1 mediates pyroptosis in diabetic cardiomyopathy. Cell Physiol Biochem. 2018 accepted.( IF 5.5)

37.Yue E, Tuguzbaeva G, Chen X, Qin Y, Li AQ, Sun X, Dong CR, Yu YH, Zahra SM, Shan QS, Jiang YN, Du ZM,Bai YL*. Anthocyanin is involved in the activation of pyroptosis in oral squamous cell carcinoma. Phytomedicine. 2018 (accepted)(IF: 3.61)

38.Song H, Yu Z, Sun X, Feng J, Yu Q, Khan H, Zhu X, Huang L, Li M, Mok MTS, Cheng ASL, Gao Y,Feng H.,Androgen receptor drives hepatocellular carcinogenesis by activating enhancer of zeste homolog 2-mediated Wnt/β-catenin signaling’ Ebiomedicine.EBioMedicine. 2018 Sep;35:155-166.(IF:6.183)

39.Feng P, Zhao L, Guo F, Zhang B, Fang L, Zhan G, Xu X, Fang Q, Liang Z,*Li B.The enhancement of cardiotoxicity that results from inhibiton of CYP 3A4 activity and hERG channel by berberine in combination with statins. Chem Biol Interact. 2018 Sep 25;293:115-123.(IF 3.2)

40.Yu Liu, jiaxin Wang, Di Huang, Bing Wang, Liangliang Li, Xiuxian Li, Ping Ni, Xingli Dong, Wei Xia, Chunxiao Yu, Wanlu Xu,Wenfeng Chu, Dan Zhao. PMLIV overexpression promotes TGF-β-associated epithelial-mesenchymal transition (EMT) and migration in MCF-7 cancer cells. Journal of Cellular Physiology. 2018 May 22; Accepted.（IF 3.923）

41.Siming Yu, Linna Li, Wei Tian, Dan Nie, Wei Mu, Fang Qiu,Yu Liu,Xinghan Liu, Xiaofeng Wang, Zhimin Du,Wenfeng Chu,Baofeng Yang. PEP06 polypeptide 30 exerts antitumour effect in colorectal carcinoma via inhibiting epithelial mesenchymal transition. British Journal of Pharmacology. 2018 May 3. doi: 10.1111h.14352. [Epub ahead of print]（IF6.810）

42.Wu D, Huang D, Li LL, Ni P, Li XX, Wang B, Han YN, Shao XQ, Zhao D,Chu WF, Li BY. J Cell Physiol. TGF-β1-PML SUMOylation- peptidyl- prolylcis- transisomerase NIMA-interacting 1 (Pin1) form a positive feed back loop to regulate cardiac fibrosis. 2018 Sep 24.（IF 3.839）

43.Hongli Shan. Heme oxygenase-1 prevents heart against myocardial infarction by attenuating ischemic injury-induced cardiomyocytes senescence.Ebiomedicine. 2018. (Accepted, IF=6.183)

44.Haihai Liang,.LncRNA PTAR promotes EMT and invasion-metastasis in serous ovarian cancer by competitively binding miR-101-3p to regulate ZEB1 expression.Molecular Cancer. 2018 August 11;17(1):119.(IF=7.776)

45.Hongli Shan.SNX17 produces anti-arrhythmic effects by preserving functional SERCA2a protein in myocardial infarction.International Journal of Cardiology. 2018 Dec 1. 272: 298-305.(IF=4.034)

46.Haihai Liang. Inhibition of lncRNA PFRL prevents pulmonary fibrosis by disrupting the miR-26a/smad2 loop.American Journal of Physiology-lung cellular and molecular physiology. 2018 Oct 1;315(4):L563-L575. (IF=4.092)

47.Haihai Liang. lncRNA PFAR promotes lung fibroblast activation and fibrosis by targeting miR-138 to regulate the YAP1/Twist axis.Molecular Therapy.2018. 26(9):2206-2217.(IF=7.008)

48.Xianxian Wu, Haiying Zhang, Wei Qi, Ying Zhang, Jiamin Li, Zhange Li, Yuan Lin, Xue Bai, Xin Liu,Xiaohui Chen, Huan Yang, Chaoqian Xu,Yong Zhang*, Baofeng Yang*. Nicotine promotes atherosclerosis via ROS NLRP3-mediated endothelial cell pyroptosis.Cell Death and Disease. 2018; 9(2):171.（IF: 5.638）

49.Jiamin Li, Qingwei Zhang, Cong Ren, Xianxian Wu, Ying Zhang, Xue Bai, Yuan Lin, Mingqi Li, Jiangbo Fu, Philipp Kopylov, Siqi Wang, Tingting Yu, Ning Wang, Chaoqian Xu,Yong Zhang*, Baofeng Yang*; Low-Intensity Pulsed Ultrasound Prevents the Oxidative Stress Induced Endothelial- Mesenchymal Transition in Human Aortic Endothelial Cells.Cell Physiol Biochem. 2018;45(4):1350-1365.（IF: 5.500）

50.Chengling Chu, Xin Liu, Xue Bai, Tong Zhao, Mengxue Wang, Ranchen Xu, Mingqi Li, Yingying Hu, Weihua Li, Lida Yang, Youyou Qin, Meng Yang, Chaoqi Yan*,Yong Zhang*,MiR-519d suppresses breast cancer tumorigenesis and metastasis via targeting MMP3.International Journal of Biological Sciences. 2018; 14(2):228-236.（IF: 4.057）

51.Xin Liu#, Tong Zhao#, Xue Bai, Mingqi Li, Jingli Ren, Mengxue Wang1, Ranchen Xu, Shuqian Zhang, Huimin Li, Yingying Hu, Liangjun Xie, Ying Zhang, Lida Yang, Chaoqi Yan*,Yong Zhang*. LOC101930370/miR-1471 axis modulates the Hedgehog signaling pathway in breast cancer. Cellular Physiology and Biochemistry. 2018;48(3):1139-1150.（IF: 5.500）

52.Naiwei Dong, Xin Liu, Tong Zhao, Lei Wang, Huimin Li, Shuqian Zhang, Xia Li, Xue Bai,Yong Zhang*, Baofeng Yang*. Apoptosis-inducing effects and growth inhibitory of a novel chalcone in human hepatic cancer cells and lung cancer cells. Biomedicine & Pharmacotherapy. 2018;105(29):195-203.（IF: 3.457）

53.Dan Xiao, Yingying Hu, Yujie Fu, Rui Wang, Haiying Zhang, Mingqi Li, Zhange Li, Ying Zhang, Lina Xuan, Xin Li, Chaoqian Xu,Yong Zhang*, Baofeng Yang*. Emodin improves glucose metabolism by targeting microRNA-20b in insulin-resistant skeletal muscle. Phytomedicine. 2018.（SCI IF: 3.61）

54.Dan Xiao, Tong Zhou, Yujie Fu, Rui Wang, Haiying Zhang, Mingqi Li, Yuan Lin, Zhange Li, Chaoqian Xu, Baofeng Yang, Ying Zhang*,Yong Zhang*. MicroRNA-17 impairs glucose metabolism in insulin-resistant skeletal muscle via repressing glucose transporter 4 expression. European Journal of Pharmacology. 2018;838:170-176.（IF: 3.04）

55.Qiang Li, Zhange Li, Yuan Lin, Hui Che, Yingying Hu, Xujuan Kang, Ying Zhang, Lihong Wang*,Yong Zhang*.High glucose promotes hepatic fibrosis via miR-32/MTA3-mediated epithelial-to-mesenchymal transition. Molecular Medicine Reports. 2018.（IF:1.922）

56.Yixiu Zhao, Xin Zhang, Jing Luan, Buchang Zhao, Na An, Na Sun, Xinhui Wang, Tao Zhao, Yanhong Sun, Zidong Donna Fua, Yan Zhang, Baofeng Yang. Shenxianshengmai oral liquid reduces myocardial oxidative stress and protects myocardium from ischemia-reperfusion injury. Cellular Physiology and Biochemistry. 2018;48:2503-2516（IF=5.500）

57.Piao XM, Gao F, Zhu JX, Wang LJ, Zhao X, Li X, Sheng MM, Zhang Y. Cucurbitacin B inhibits tumor angiogenesis by triggering the mitochondrial signaling pathway in endothelial cells. Int J Mol Med. 2018 Aug;42(2):1018-1025. doi: 10.3892/ijmm.2018.3647. Epub 2018 Apr 30（IF 2.784）

58.Meiling Zhang, Xin Li, Hangfei Liang, Huqiang Cai, Xueling Hu, Yu Bian, Lei Dong, Lili Ding, Libo Wang, Bo Yu, Yan Zhang, Yao Zhang. Semen Cassiae Extract Improves Glucose Metabolism by Promoting GlUT4 Translocation in the Skeletal Muscle of Diabetic Rats, Frontiers in Pharmacology. 2018 Apr 4;9:235. doi: 10.3389/fphar.2018.00235. eCollection 2018.（IF 3.831）

59.Ying Zhang*, Xue Liu*, Lu Zhang*, Xuelian Li, Zhongqiu Zhou, Lei Jiao, Yingchun Shao, Mengmeng Li, Bing Leng, Yuhong Zhou, Tianyi Liu, Qiushuang Liu, Hongli Shan1, Zhimin Du. Metformin Protects against H2O2-Induced Cardiomyocyte Injury by Inhibiting the miR-1a-3p/GRP94 Pathway. Mol Ther Nucleic Acids. 2018 Sep 6;13:189-197.（IF 5.660）

60.Zhang L#, Yin H#, Jiao L#, Liu T, Gao Y, Shao Y, Zhang Y, Shan H, Zhang Y* and Yang B*. Abnormal Downregulation of Caveolin-3 Mediates the Pro-Fibrotic Action of MicroRNA-22 in a Model of Myocardial Infarction. Cell Physiol Biochem. 2018;45:1641-1653.（并列一作，IF 5.500）