周伟伟，硕士/博士生导师，主要研究方向为生物医学信息学、免疫信息学。以第一作者，共同第一作者在《Nature Communications》（ESI 高被引）、《Nucleic Acids Research》《Communications Biology》等期刊发表多篇论文，其中 SCI 影响因子＞10 的论文 8 篇。

教育经历

2020.09 - 2025.07    哈尔滨医科大学    生物医学工程                 硕博连读

2015.09 - 2020.07    哈尔滨医科大学    生物技术（生物信息）    学士

工作经历

2025.07 - 至今          哈尔滨医科大学    医工交叉学院        讲师、优才博士后

代表性论文

1）Weiwei Zhou^#, Minghai Su^#, Tiantongfei Jiang^#, Qingyi Yang^#, Qisen Sun, Kang Xu, Jingyi Shi,Changbo Yang,Na Ding*, Yongsheng Li*, Juan Xu*. SORC: an integrated spatial omics resource in cancer. 2024 Jan. Nucleic Acids Research.

2）Weiwei Zhou^#, Minghai Su^#, Tiantongfei Jiang^#, Yunjin Xie, Jingyi Shi, Yingying Ma,Kang Xu,Gang Xu, Yongsheng Li*, Juan Xu*. Cancer Stemness Online: A resource for investigating cancer stemness and associations with immune response. 2024 May. Genomics, Proteomics & Bioinformatics.

3）Weiwei Zhou^#, Qiuling Jie^#, Tao Pan^#, Jingyi Shi, Tiantongfei Jiang,Ya Zhang,Na Ding,Juan Xu*, Yanlin Ma*, Yongsheng Li*. Single-cell RNA binding protein regulatory network analyses reveal oncogenic HNRNPK-MYC signalling pathway in cancer. 2023 Jan. Communications Biology.

4）Weiwei Zhou^#, Qingyi Yang^#, Jiyu Guo^#, Si Li^#, Minghai Su, Feng Leng, Yueying Gao,Luan Wen,Kefan Liu,Tiantongfei Jiang*, Yongsheng Li*, Juan Xu*. SMTdb: A comprehensive spatial meta-transcriptome resource in cancer. Molecular Biology and Evolution.

5）Tiantongfei Jiang^#, Weiwei Zhou^#, Qi Sheng^#, Jiaxin Yu^#, Yunjin Xie,Na Ding,Yunpeng Zhang*, Juan Xu*,Yongsheng Li* . ImmCluster: an ensemble resource for immunology cell type clustering and annotations in normal and cancerous tissues. 2023 Jan. Nucleic Acids Research.

6）Tiantongfei Jiang^#, Weiwei Zhou^#, Zhenghong Chang^#, Haozhe Zou, Jing Bai,Qisen Sun,Tao Pan, Juan Xu*,Yongsheng Li*,Xia Li*. ImmReg: the regulon atlas of immune-related pathways across cancer types. 2021 Dec.

7）Min Su^#, Tao Pan^#, Qiu‑Zhen Chen^#, Weiwei Zhou^#, Yi Gong, Gang Xu, Huan‑Yu Yan, Xia Li*, Murray J. Cairns*,Xi Wang*,Yong‑Sheng Li*. Data analysis guidelines for single-cell RNA-seq in biomedical studies and clinical applications. 2022 Dec. MILITARY MEDICAL RESEARCH.

8）Zishan Wang^#, Jiaqi Yin^#,Weiwei Zhou^#, Jing Bai^#, Yunjin Xie, Kang Xu,Xiangyi Zheng,Jun Xiao,Li Zhou,Xiaolin Qi, Yongsheng Li*,Xia Li*,Juan Xu*. Complex impact of DNA methylation on transcriptional dysregulation across 22 human cancer types. 2020 Mar. Nucleic Acids Research.

9）Yongsheng Li^#*, Tiantongfei Jiang^#,Weiwei Zhou^#, Junyi Li, Xinhui Li,Qi Wang,Xiaoyan Jin,Jiaqi Yin,Liuxin Chen,Yunpeng Zhang, Juan Xu*,Xia Li*. Pan-cancer characterization of immune-related lncRNAs identifies potential oncogenic biomarkers. 2020 Feb. Nature Communications.

10）Jiwei Zhang^#, Tao Pan^#,Weiwei Zhou^#, Ya Zhang, Gang Xu,Qi Xu,Si Li,Yueying Gao,Zhengtao Wang, Juan Xu*,Yongsheng Li*. Long noncoding RNA LINC01132 enhances immunosuppression and therapy resistance via NRF1/DPP4 axis in hepatocellular carcinoma. 2022 Sep. Journal of Experimental & Clinical Canicer Research.

11）Yunjin Xie^#, Weiwei Zhou^#, Jingyi Shi^#, Mengjia Xu, Zijing Lin,Donghao Li,Jianing Li, Shujun Cheng*,Tingting Shao*,JuanXu*. A global database for modeling tumor-immune cell communication. 2023 Jul. Scientific Data

12）Si Li^#, Weiwei Zhou^#, Donghao Li^#, Tao Pan, Jing Guo,Haozhe Zou,Zhanyu Tian,Kongning, Juan Xu*,Xia Li*,Yongsheng Li*. Comprehensive characterization of human-virus protein-protein interactions reveals disease comorbidities and potential antiviral drugs. 2022 Mar. Computational and Structural Biotechnology Journal.

科研项目

1. 黑龙江省自然科学基金项目 面上项目，10万，主持

2. 黑龙江省博士后择优资助，10万，主持

3. 中国博士后科学基金面上资助（78批），8万，主持

4. 引进人才科研启动金，100万，主持