获国家及省部级奖项
(1)水源性高碘危害流性特征、防治策略及发病机制研究,黑龙江省医药卫生科学技术奖一等奖;2019年
(2)水源性高碘危害流性特征、防治策略及发病机制研究,黑龙江省科学技术进步二等奖;2019年
(3)中国碘缺乏病监测与防治策略,获教育部科技进步一等奖;2006年
(4)盐碘标准物的研制及应用,获黑龙江省医药卫生科技进步一等奖,黑龙江省政府科技进步二等奖,国家教育部提名科技进步二等奖。2006年
(5)碘锌缺乏在地克病病因及发病中的作用,获黑龙江省教委科技进步一等奖,黑龙江省政府科技进步三等奖;2004年
(6)恒温消解仪的研制和恒温消解尿碘测定方法的建立,获黑龙江省医药卫生科技进步一等奖,黑龙江省政府科技进步二等奖;1995年
(7)碘硒联合缺乏对脑发育影响的实验研究,获黑龙江省教委科技进步一等奖,黑龙江省政府科技进步三等奖; 1995年
(8)妊娠不同时期服用碘油对脑发育的影响,获黑龙江省医药卫生科技进步一等奖;1993年
(9)缺碘地区杨林乡孕妇流产、早产、死亡、新生儿死亡率情况调查,获黑龙江省医药卫生科技进步二等奖;
(10)桦川县集贤村地甲病流行病学调查,获黑龙江省医药卫生科技进步一等奖
(11)茶砖加碘防治碘缺乏病,获西藏自治区政府科技进步三等奖,西藏医药卫生科技进步一等奖;1989年
(12)克汀病大鼠动物模型的复制,获黑龙江省医药卫生科技进步一等奖,黑龙江省政府科技进步三等奖;1987年。
近5年发表的SCI收录论文
1. Du Y, Liu P, Zhang W, et al. Serum thyroglobulin as a biomarker of iodine excess and thyroid disease occurrence in adults[J]. J Trace Elem Med Biol. 2023, 78:127172.
2. Chen Y, Zhang X, Li D, et al. Automatic segmentation of thyroid with the assistance of the devised boundary improvement based on multicomponent small dataset[J]. Appl Intell (Dordr). 2023, 15:1-16.
3. Chen Y, Li D, Zhang X et al. A devised thyroid segmentation with multi-stage modification based on Super-pixel U-Net under insufficient data. Ultrasound Med Biol[J]. 2023, 49(8):1728-1741.
4. Hou X, Zhao M, Li J, et al. Distribution of iodine concentration in drinking water in China mainland and influence factors of its variation[J]. Sci Total Environ. 2023, 892:164628.
5. Qian TT, Sun R, Liu LC et al. Relationship between Dining Place, Iodine Source, and Iodine Nutrition in School-Age Children: A Cross-Sectional Study in China[J]. Biomed Environ Sci. 2023, 36(1):10-23.
6. Wang D, Li P, Liu L, et al. The effect and mechanism of excessive iodine on the endothelial function of human umbilical vein endothelial cells[J]. Environ Toxicol. 2023, 38(1):136-145.
7. Jin M, Zhou Z, Zhang L, et al. Effects of Excessive Iodine on the BDNF-TrkB Signaling Pathway and Related Genes in Offspring of EAT Rats[J]. Biol Trace Elem Res. 2023, 201(2):776-785.
8. Fan L, Du Y, Meng F, et al. How to Decide the Iodine Content in Salt for a Country-China as an Example[J]. Nutrients. 2022, 14(21):4606.
9. Sun R, Liu L, Qian T, et al. Protection of Vitamin C on Oxidative Damage Caused by Long-Term Excess Iodine Exposure in Wistar Rats[J]. Nutrients. 2022, 14(24):5245.
10. An S, Fan L, Li M, et al. Relationship between water iodine and children's goiters[J]. Br J Nutr. 2022,128(9):1798-1805.
11. Li F, Wan S, Zhang L, Li B, et al. A Meta-Analysis of the Effect of Iodine Excess on the Intellectual Development of Children in Areas with High Iodine Levels in their Drinking Water[J]. Biol Trace Elem Res. 2022, 200(4):1580-1590.
12. Du Y, Liu P, Meng F, et al.What Iodine Intervention Measures Should Be Taken in Different Water Iodine Areas? Evidence from a Cross-sectional Chinese Survey[J]. Biol Trace Elem Res. 2022 ,200(11):4654-4663.
13. Zhang L, Fan L, Li F, et al. Study on the Effect of Different Iodine Intake on Hippocampal Metabolism in Offspring Rats[J]. Biol Trace Elem Res. 2022, 200(10):4385-4394.
14. Fan LJ, Gao YY, Meng FG, et al. Time Series and Spatial Epidemiological Analysis of the Prevalence of Iodine Deficiency Disorders in China[J]. Biomed Environ Sci. 2022, 35(8):735-745.
15. Sun R, Fan L, Du Y, et al.The relationship between different iodine sources and nutrition in pregnant women and adults[J]. Front Endocrinol (Lausanne). 2022, 13:924990.
16. Zhou Z, Liu L, Jin M, et al. Relationships between the serum TPOAb and TGAb antibody distributions and water iodine concentrations, thyroid hormones and thyroid diseases: a cross-sectional study of 2503 adults in China[J]. Br J Nutr. 2022, 25:1-11.
17. Li J, He Y, Ren B, et al. The Thyroid Condition and Residual Clinical Signs in 31 Existing Endemic Neurological Cretins After 42 Years of Iodine Supplementation in China[J]. Front Endocrinol (Lausanne). 2022,13:911487.
18. Sun R, Qian TT, Liu LC, et al.Effect of Iodine Supplementation on Iodine Nutrition and Thyroid Function in Pregnant Women: A Cross-Sectional Study[J]. Biomed Environ Sci. 2022, 35(7):641-647.
19. An S, Li W, Wang X, et al. Study on influential factors and reference values for thyroid volume in Chinese children aged 6-12 years[J]. Br J Nutr. 2022,11:1-9.
20. Ren B, Wan S, Wu H, et al. Effect of different iodine levels on the DNA methylation of PRKAA2, ITGA6, THEM4 and PRL genes in PI3K-AKT signaling pathway and population-based validation from autoimmune thyroiditis patients[J]. Eur J Nutr. 2022, 61(7):3571-3583.
21. Fan L, Meng F, Sun Q, et al. Assessment of Sustainable Elimination Criteria for Iodine Deficiency Disorders Recommended by International Organizations[J]. Front Nutr. 2022, 9:852398.
22. Liu L, Qian T, Sun R, et al. Comparative Analysis of Five Correction Methods for Thyroid Volume by Ultrasound and Their Recommended Reference Values in Chinese Children Aged 8-10 Years[J]. Br J Nutr. 2022, 13:1-28.
23. Qu M, Wan S, Wu H, et al. The Whole Blood DNA Methylation Patterns of Extrinsic Apoptotic Signaling Pathway Related Genes in Autoimmune Thyroiditis among Areas with Different Iodine Levels[J]. Br J Nutr. 2022, 9:1-35.
24. Liu L, Liu L, Li M, et al. Study on association between height, weight, iodine supplementation and thyroid volume[J]. Br J Nutr. 2022, 127(9):1358-1366.
25. Lv C, Gao Y, Yao J, et al. High Iodine Induces the Proliferation of Papillary and Anaplastic Thyroid Cancer Cells via AKT/Wee1/CDK1 Axis[J]. Front Oncol. 2021, 11:622085.
26. Fan L, Meng F, Gao Y, et al. Insufficient iodine nutrition may affect the thyroid cancer incidence in China[J]. Br J Nutr. 2021,126(12):1852-1860.
27. Sun Q, Zhao H, Liu Z, et al. Identifying potential metabolic tissue biomarkers for papillary thyroid cancer in different iodine nutrient regions[J]. Endocrine. 2021,74(3):582-591.
28. Wang D, Wan S, Liu P, et al. Relationship between excess iodine, thyroid function, blood pressure, and blood glucose level in adults, pregnant women, and lactating women: A cross-sectional study[J]. Ecotoxicol Environ Saf. 2021, 208:111706.
29. Fan L, Tian Q, Xiu C, et al. High Iodine Nutrition May Be a Risk Factor for Cervical Lymph Node Metastasis in Papillary Thyroid Cancer Patients[J]. Ann Nutr Metab. 2021, 77(2):90-99.
30. Ren B , Wan S , Liu L , et al. Distributions of serum thyroid-stimulating hormone in 2020 thyroid disease-free adults from areas with different iodine levels: a cross-sectional survey in China[J]. Journal of Endocrinological Investigation, 2021, 44(5):1001-1010.
31.Tian C , Bu Y , Ji C, et al. Iodine Nutrition and the Prevalence Status of Thyroid Nodules in the Population: a Cross-sectional Survey in Heilongjiang Province, China[J]. Biological Trace Element Research, 2021, 199(4):1-9.
32. Nie GY, Wang R, Liu P, et al. Mild Anemia May Affect Thyroid Function in Pregnant Chinese Women During the First Trimester[J]. Front Endocrinol (Lausanne). 2021, 12:772917.
33. Liu L, Liu P, Lin Q, et al. Iodine nutrition status of women after 10 years of Lipiodol supplementation: a cross-sectional study in Xinjiang, China[J]. The British journal of nutrition, 2020, 126(1):1-31.
34. Wan S , Qu M , Wu H , et al. Autoimmune Thyroid Diseases after 25 years of Universal Salt Iodization: An Epidemiologic Study of Chinese Adults in Areas with Different Water Iodine Levels[J]. British Journal Of Nutrition, 2020:1-30.
35. Guan H , Li X , Lu J , et al. Aberrant Methylation of Suppressor of Cytokine Signaling 1 (SOCS1) Gene as a Biomarker for Early Prediction and Diagnosis of Bladder Cancer[J]. Clinical laboratory, 2020, 66(5/2020).
36. Qu M , Wan S , Ren B , et al. Association between TSHR gene methylation and papillary thyroid cancer: a meta-analysis[J]. Endocrine, 2020, 69(3):508-515.
37. Wu H , Wan S , Qu M , et al. The Relationship between PTPN22 R620W Polymorphisms and the Susceptibility to Autoimmune Thyroid Diseases: An Updated Meta-analysis[J]. Immunological Investigations, 2020(2):1-14.
38. Pan Y , Yun W , Shi B , et al. Downregulation of miR-146b-5p via iodine involvement repressed papillary thyroid carcinoma cell proliferation[J]. Journal of Molecular Endocrinology, 2020, 65(2).
39. Cheng X A , Qian H B , Hong J , et al. Strong Correlation of Abnormal Serum and Urinary Iodine Levels with Papillary Thyroid Cancer: A Case-control Study[J]. Biomedical and Environmental Sciences, 2020, 33( 1):62-67.
40. Yu T , Jing M , Y Gao, et al. Study on the relationship between hyperthyroidism and vascular endothelial cell damage[J]. Scientific Reports, 2020, 10(1).
41. Guan Y , Liu L , Jia Q , et al. The Role of Cell Growth-Related Gene Copy Number Variation in Autoimmune Thyroid Disease[J]. Biological Trace Element Research, 2020, 195(2).
42. Liu J , Liu L , Jia Q , et al. Effects of Excessive Iodine Intake on Blood Glucose, Blood Pressure, and Blood Lipids in Adults[J]. Biological Trace Element Research, 2019.
43. Liu L , Liu J , Wang D , et al. Effect of Urinary Iodine Concentration in Pregnant and Lactating Women, and in Their Infants Residing in Areas with Excessive Iodine in Drinking Water in Shanxi Province, China[J]. Biological Trace Element Research, 2019.
44. Zhang W , Gao Y , Yu G , et al. Progress in the prevention and control of water-borne arsenicosis in China[J]. International Journal of Environmental Health Research, 2019:1-10.
45. Chunlei, Chunyuan, Tian et al.. Determination of Reference Intervals of Ratios of Concentrations of Urinary Iodine to Creatinine and Thyroid Hormone Concentrations in Pregnant Women Consuming Adequate Iodine in Harbin, Heilongjiang Province.[J]. Biological trace element research, 2019.
46. Zhang W , Cui X , Gao Y , et al. Role of pigment epithelium-derived factor (PEDF) on arsenic-induced neuronal apoptosis[J]. Chemosphere, 2019, 215(JAN.):925-931.
出版论著
1.《中国水源性高碘危害防治与实践》(人民卫生出版社)
2.《2014年中国碘缺乏病监测》(人民卫生出版社)
3.《2011年中国碘缺乏病监测》(人民卫生出版社)
4.《碘缺乏病防治手册》(人民卫生出版社)
5.《2005年中国碘缺乏病监测》(人民卫生出版社)
6.《2002年中国碘缺乏病监测》(人民卫生出版社)
7.《97中国碘缺乏病监测》(人民卫生出版社)
8.《95中国碘缺乏病监测》(人民卫生出版社)
9.《地方性克汀病研究进展》(新疆人民出版社)
10.《碘缺乏病防治技术大全》(中国环境出版社)
11.《碘缺乏病》(黑龙江科学技术出版社)
12.《碘缺乏病防治知识百题》(内部发行)
研制国家及行业标准
1.《碘缺乏地区和适碘地区的划定》卫生行业标准 WS/T 669-2020
2.《血清中碘的测定砷铈催化分光光度法》卫生行业标准WS/T 572-2017
3.碘缺乏病病区划分GB 16005-2009
4.地方性甲状腺肿诊断标准 WS 276-2007
5.盐碘现场半定量检测包质量评定标准 GB 17022-1997
发明专利
1.一种盐碘标准物的制造方法(发明专利)
2.碘缺乏病科普宣传扑克(外观专利)
3.盐碘快速定量检测装置及检测方法(发明专利)
4.井矿盐中碘含量快速定量检测方法(发明专利)
5.一种血清碘定量测定试剂盒(发明专利)